Guidelines for acute care

Join the movement for quality, equitable sickle cell treatment. 

NIH EVIDENCE-BASED MANAGEMENT OF SICKLE CELL DISEASE

NIH full recommendations

Click the image at left for a PDF of the full 161-page NIH recommendations.

 

This link will take you directly to the full document at NIH's site.  

NIH Quick Guide to Recommendations

"The purpose of this Guide to Recommendations is to provide clinicians with a digital resource of the treatment recommendations extracted from the full report. For more information, please refer to the full report. . . ."

Click the image at right for a pdf of the 48-page Quick Guide. This link will take you directly to the Quick Guide document at NIH's site.  

NIH GUIDELINES: ACUTE CARE BREAKOUT

For ease-of-access, this section contains a breakout of individual acute complications of sickle cell with links to corresponding PDFs from the Quick Guide and the full recommendations.

What does the patient report? Remember: LABS ASSESS FOR COMPLICATIONS. Labs do not rule out or confirm pain crisis or a patient's level of pain!

Acute Chest Syndrome: Quick  Full   Respiratory Algorithm

Acute Stroke: Quick  Full

Anemia: Quick  Full

Fever: Quick  Full

Hepatobiliary: Quick  Full

Multi-System Organ Failure: Quick  Full

Ocular Conditions: Quick  Full

Priapism: Quick  Full

Renal Failure: Quick  Full

Splenic Sequestration: Quick  Full

Vaso-occlusive crisis/pain episode: Quick  Full

Duke respiratory.png

Click here for an algorithm to assist with diagnosis

Developed by the NC Division of Public Health; the comprehensive sickle cell centers at Carolinas Health Care, Duke University, East Carolina University, University of North Carolina at Chapel Hill, Mission, and Wake Forest University; and primary care physicians from across North Carolina

 
 
AMERICAN SOCIETY OF HEMATOLOGY
2020 SICKLE CELL GUIDELINES

Cardiopulmonary & Kidney Disease

CPK Guideline Snapshot

Full ASH CPK Guideline (pdf)

Full ASH CPK Guideline (web)

About the CPK Guideline ( 2:40 - video)

Acute & Chronic Pain

Pain Guideline Snapshot

Full ASH Pain Guideline (pdf)

Full ASH Pain Guideline (web)

About the Pain Guideline (3:42 - video)

Cerebrovascular Disease

Cerebrovascular Guideline Snapshot

Full ASH Cerebrovascular Guideline (pdf)

Full ASH Cerebrovascular Guideline (web)

About the Cerebrovascular Guideline (2:43 - video)

Transfusion Support

Transfusion Guideline Snapshot

Full ASH Transfusion Guideline (pdf)

Full ASH Transfusion Guideline (web)

About the Transfusion Guideline (2:57 - video)

Visit ASH for full information on the new ASH sickle cell guidelines, apps, pre-made presentations, and more. 

 
ASH POCKET GUIDES FOR ACUTE
AND NON-ACUTE CARE MANAGEMENT
ASH POCKET GUIDE - MANAGEMENT OF ACUTE COMPLICATIONS OF SICKLE CELL 

Click the image to access a PDF of ASH's Management of Acute Complications of Sickle Cell Disease pocket guide. 

Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014. (Click here to go directly to ASH's web site for links to all its sickle cell pocket guides.)

ACCESS ALL ASH POCKET GUIDES FOR  MANAGING SICKLE CELL

Click here to go directly to ASH's web site for links to all the sickle cell pocket guides. The following links will take you to individual PDFs for download.

 

Cardiopulmonary and Kidney Disease in Sickle Cell Disease: Screening and Management
This pocket guide includes key recommendations from the American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease, available soon in Blood Advances.

Health Maintenance and Management of Chronic Complications of Sickle Cell Disease
Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014

Hydroxyurea and Transfusion Therapy for the Treatment of Sickle Cell Disease
Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014

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Empowering medical professionals to implement quality sickle cell treatment. Amplifying the patient's voice in care.