Guidelines for acute care
Join the movement for quality, equitable sickle cell treatment.
NIH EVIDENCE-BASED MANAGEMENT OF SICKLE CELL DISEASE
NIH full recommendations
Click the image at left for a PDF of the full 161-page NIH recommendations.
This link will take you directly to the full document at NIH's site.
NIH Quick Guide to Recommendations
"The purpose of this Guide to Recommendations is to provide clinicians with a digital resource of the treatment recommendations extracted from the full report. For more information, please refer to the full report. . . ."
​
Click the image at right for a pdf of the 48-page Quick Guide. This link will take you directly to the Quick Guide document at NIH's site.
NIH GUIDELINES: ACUTE CARE BREAKOUT
For ease-of-access, this section contains a breakout of individual acute complications of sickle cell with links to corresponding PDFs from the Quick Guide and the full recommendations.
What does the patient report? Remember: LABS ASSESS FOR COMPLICATIONS. Labs do not rule out or confirm pain crisis or a patient's level of pain!
Click here for an algorithm to assist with diagnosis
Developed by the NC Division of Public Health; the comprehensive sickle cell centers at Carolinas Health Care, Duke University, East Carolina University, University of North Carolina at Chapel Hill, Mission, and Wake Forest University; and primary care physicians from across North Carolina
AMERICAN SOCIETY OF HEMATOLOGY
2020 SICKLE CELL GUIDELINES
Cerebrovascular Disease
Cerebrovascular Guideline Snapshot
Full ASH Cerebrovascular Guideline (pdf)
Full ASH Cerebrovascular Guideline (web)
About the Cerebrovascular Guideline (2:43 - video)
Transfusion Support
Transfusion Guideline Snapshot
Full ASH Transfusion Guideline (pdf)
Full ASH Transfusion Guideline (web)
About the Transfusion Guideline (2:57 - video)
Visit ASH for full information on the new ASH sickle cell guidelines, apps, pre-made presentations, and more.
ASH POCKET GUIDES FOR ACUTE
AND NON-ACUTE CARE MANAGEMENT
ASH POCKET GUIDE - MANAGEMENT OF ACUTE COMPLICATIONS OF SICKLE CELL
Click the image to access a PDF of ASH's Management of Acute Complications of Sickle Cell Disease pocket guide.
Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014. (Click here to go directly to ASH's web site for links to all its sickle cell pocket guides.)
ACCESS ALL ASH POCKET GUIDES FOR MANAGING SICKLE CELL
Click here to go directly to ASH's web site for links to all the sickle cell pocket guides. The following links will take you to individual PDFs for download.
Cardiopulmonary and Kidney Disease in Sickle Cell Disease: Screening and Management
This pocket guide includes key recommendations from the American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease, available soon in Blood Advances.
​
Health Maintenance and Management of Chronic Complications of Sickle Cell Disease
Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014
​
Hydroxyurea and Transfusion Therapy for the Treatment of Sickle Cell Disease
Presented by ASH in 2014, adapted from the National Heart, Lung, and Blood Institute's Evidence Based Management of Sickle Cell Disease: Expert Panel Report, 2014
​
Download the apps:
For iOS
For Android
Web version of the apps
SOURCES: https://www.minorityhealth.hhs.gov/sicklecell/, https://www.nhlbi.nih.gov/health-topics/evidence-based-management-sickle-cell-disease, https://www.nhlbi.nih.gov/sites/default/files/media/docs/Evd-Bsd_SickleCellDis_Rep2014.pdf, https://www.hematology.org/Clinicians/Guidelines-Quality/Quick-Reference.aspx, https://sickleemergency.duke.edu/educational-resources/videos, https://www.ahrq.gov/sites/default/files/wysiwyg/professionals/systems/hospital/esi/esihandbk.pdf, https://sickleemergency.duke.edu/sites/default/files/Hypoxia%20SCD%20122014-Final.pdf